
While four teams can clinch playoff berths this weekend, the 49ers are the only that has locked up a spot in the NFL playoff bracket. However, there is another incentive involved in the Week 15 NFL schedule since the Niners can also clinch the NFC West. A win over the Cardinals would make San Francisco the first team since Seattle in 2013-14 to win back-to-back NFC West crowns. San Francisco is a 12.5-point favorite in the Week 15 NFL odds and is the only double-digit favorite per the Week 15 NFL spreads.
The 49ers are 2-2 against the spread when favored by double-digits this season, while Arizona is 1-2 ATS as an underdog of 10-plus points. While San Francisco notching the divisional banner is in little doubt in most people’s eyes, making Week 15 NFL picks against the spread could be a risky proposition. All of the Week 15 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 15 NFL picks now.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 15 of the 2023 NFL season on an incredible 176-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 30-21 roll on top-rated NFL picks since Week 7 of last season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, it has turned its attention to the latest Week 15 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.
Top Week 15 NFL predictions
We can tell you one of the model’s strongest Week 15 NFL picks is that the Browns (-3) cover at home against the Bears. Chicago is coming off back-to-back wins over Minnesota and Detroit, but it has not won three straight games since 2020. The Bears are just 2-5 in their seven road games this season and 2-9 in their last 11 road games dating back to last year.
Cleveland has been a difficult team to beat at home, winning and covering the spread in nine of its last 11 games. The Browns can take another pivotal step toward a playoff berth following a 31-27 win over Jacksonville last week that put them in line for the No. 5 seed in the AFC. Veteran quarterback Joe Flacco threw for 311 yards and three touchdowns in that game, a big reason why the Browns are covering in almost 60% of the model’s latest simulations. See which other teams to pick here.
Another one of its Week 15 NFL predictions: The Seahawks (+3) cover the spread versus the Eagles. Pete Carroll has had the Eagles’ number throughout his tenure as Seahawks head coach, going 7-0 straight up and 6-1 against the spread versus Philadelphia. The three home wins for Seattle during this stretch have all been by double-digits, with a 14-point average margin of victory. Philadelphia also enters this contest with back-to-back ATS losses over the last two weeks, which matches the number of ATS defeats it had over the first 11 games of the season.
In 2023, Seattle’s defense leads the NFL in hurries (53) and ranks in the top five in pressure rate (24.9%). That’s a cause for concern for Jalen Hurts, who is susceptible to the pass rush. Hurts has fumbled in seven straight games, while just three players have more turnovers than his 15 this season. The model has Seattle sacking Hurts three times. With Philadelphia’s offense contained, the Seahawks (+4) cover well over 50% of the time. See which other teams to pick here.
How to make Week 15 NFL picks
The model has also made the call on who wins and covers in every other game on the Week 15 NFL schedule and just revealed two more coveted A-rated picks. You can only get every pick for every game at SportsLine.
So what NFL picks can you make with confidence, and which A-rated picks should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000 since its inception, and find out.
Week 15 NFL odds, lines, spreads
Get full NFL picks at SportsLine
Saturday, Dec. 16
Vikings at Bengals (-3.5, 40.5)
Sunday, Dec. 17
Bears at Browns (-3, 38)
Buccaneers at Packers (-3.5, 42)
Chiefs at Patriots (+8, 37)
49ers at Cardinals (+12.5, 48)
Commanders at Rams (-6.5, 50.5)
Ravens at Jaguars (+3, 42.5)
Monday, Dec. 18
Eagles at Seahawks (+3, 47.5)
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Author: CBS Sports Staff
December 16, 2023 | 1:20 pm
